Proteogenomics

Proteogenomics is a cutting-edge field that merges genomics and proteomics to provide a comprehensive understanding of biological systems at the molecular level. A key application of proteogenomics is the discovery of variant and personalized epitopes for immunotherapies.

By integrating genomic and proteomic data, we can identify patient-specific variants in protein-coding regions and detect these personalized epitopes in patient-derived samples. This approach is particularly valuable in cancer immunotherapy. Using advanced proteogenomics methods, we can discover new epitopes resulting from specific mutations in a patient’s tumor. This enables the design of targeted immunotherapies that precisely attack cancer cells without harming normal tissue.

Furthermore, we validate the presence of these neoepitopes at the protein level in patient samples, accelerating the development of highly effective, personalized immunotherapies. Through our services, we aim to advance personalized medicine and provide new hope for patients with complex and diverse genetic backgrounds.