Biomarkers

Biomarkers are measurable indicators of biological processes, conditions, or diseases. They can be molecules such as proteins, genes, metabolites, or cells, and provide valuable information about the state of an individual’s health. Biomarkers are widely used in medicine for diagnosis, prognosis, and monitoring of diseases, as well as in the development of targeted therapies.

HLA peptides are an interesting novel biomarker source, as they are found in blood at high concentrations. While the use of blood-soluble HLA complexes (sHLA) has been hypothesized by academia for some time, the implementation requires deep knowledge of HLA peptide presentation in health and disease. With Alithea’s HLA Compass HLA peptide database, Alithea is in the unique position to develop sHLA based biomarkers for pre-clinical and clinical use.

If you are interested in the discovery or validation of HLA peptide biomarkers, please reach out to us below: